Bisphosphonate related osteonecrosis of the jaws: report of two cases.
10.5624/isd.2011.41.3.129
- Author:
Jin Woo HAN
1
Author Information
1. Department of Oral and Maxillofacial Radiology and Research Institute of Oral Science, College of Dentistry, Gangneung-Wonju National University, Gangneung, Korea. hanjw@gwnu.ac.kr
- Publication Type:Case Report
- Keywords:
Bisphosphonate;
Osteonecrosis;
Tomography, X-ray Computed;
Osteoporosis
- MeSH:
Bisphosphonate-Associated Osteonecrosis of the Jaw;
Diphosphonates;
Humans;
Jaw;
Neoplasm Metastasis;
Osteomyelitis;
Osteonecrosis;
Osteoporosis;
Tomography, X-Ray Computed
- From:Imaging Science in Dentistry
2011;41(3):129-134
- CountryRepublic of Korea
- Language:English
-
Abstract:
Bisphosphonates are compounds used to treat osteoporosis and malignant bone metastasis. Despite the benefits related to the use of these medications, osteonecrosis of the jaws is a significant complication in a subset of patients receiving these drugs. This complication occurs either spontaneously or after a simple dento-alveolar surgery. Recently there were two patients who showed the features of bisphosphonate related osteonecrosis of the jaws (BRONJ) in Gangneung-Wonju National University Dental Hospital. The patients revealed the clinical and radiological features of classical osteomyelitis. This report presents two cases of BRONJ which were examined by plain radiography and computed tomography.