Endoscopic Ultrasound Guided Fine Needle Aspiration Biopsy in Diagnosis of Pancreatic and Peripancreatic Lesions: A Single Center Experience in Korea.
- Author:
Chang Yun HWANG
1
;
Sang Soo LEE
;
Tae Jun SONG
;
Sung Hoon MOON
;
Don LEE
;
Do Hyun PARK
;
Dong Wan SEO
;
Sung Koo LEE
;
Myung Hwan KIM
Author Information
- Publication Type:Original Article
- Keywords: EUS-FNA; Pancreatic neoplasms; Peripancreatic mass; Diagnostic accuracy
- MeSH: Biopsy; Endoscopic Ultrasound-Guided Fine Needle Aspiration; Humans; Korea; Medical Records; Multivariate Analysis; Pancreatic Neoplasms; Retrospective Studies; Sensitivity and Specificity
- From:Gut and Liver 2009;3(2):116-121
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND/AIMS: Although endoscopic ultrasound guided fine needle aspiration (EUS-FNA) has been introduced and its use has been increasing in Korea, there have not been many reports about its performance. The aim of this study was to assess the utility of EUS-FNA without on-site cytopathologist in establishing the diagnosis of solid pancreatic and peripancreatic masses from a single institution in Korea. METHODS: Medical records of 139 patients who underwent EUS-FNA for pancreatic and peripancreatic solid mass in the year 2007, were retrospectively reviewed. By comparing cytopathologic diagnosis of FNA with final diagnosis, sensitivity, specificity, and accuracy were determined, and factors influencing the accuracy as well as complications were analyzed. RESULTS: One hundred twenty out of 139 cases had final diagnosis of malignancy. Sensitivity, specificity, and accuracy of EUS-FNA were 82%, 89%, and 83%, respectively, and positive and negative predictive values were 100% and 46%, respectively. As for factors influencing the accuracy of FNA, lesion size was marginally significant (p-value 0.08) by multivariate analysis. CONCLUSIONS: EUS-FNA performed without on-site cytopathologist was found to be accurate and safe, and thus EUS-FNA should be a part of the standard management algorithm for pancreatic and peripancreatic mass.
