Evaluation of factors affecting sensory neural hearing loss.
- Author:
Seong Chul HONG
1
;
Seong wook BAE
;
Jong Young LEE
Author Information
1. Department of Preventive Medicine, College of Medicine, Kyungpuk National University, Korea.
- Publication Type:Original Article
- Keywords:
Hearing loss;
SNHL;
cardiovascular
- MeSH:
Blood Platelets;
Body Mass Index;
Cholesterol;
Ear;
Hearing Loss*;
Hearing*;
Logistic Models;
Risk Factors;
Viscosity
- From:Korean Journal of Preventive Medicine
1998;31(2):249-264
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Reports on a potential relationship between sensory neural hearing loss(SNHL) and cardiovascular or hematologic factor show that the results are controversial. A detailed analysis of risk factors in the development of SNHL was carried out in 3,050 non-noise exposed healthy worker. The mean hearing threshold of both ears at 500, 1000, 2000, 4000, 8000Hz was measured and the effect of age, possible cardiovascular risk factor and hematologic factor (blood viscosity and hemostatic factors) on SNHL were evaluated. First, each of these were associated with loss of hearing sensitivity when univariately and multivariatively analysed. In a multiple regression model, age, sex, body mass index, WBC and total cholesterol level were independently associated with the mean of hearing sensitivity decrease at 4000 and 8000Hz. Second, study subjects were divided into two group (normal vs SNHL) and we compare the possible risk between both groups, and analysed univariate and multivariative logistic model. In a multiple logistic regression model, age, sex, body mass index, WBC and total cholesterol level, total protein, platelet were independently associated with SNHL. Our results show that we have some reliable indices of susceptibility to SNHL using cardiovascular measures or biochemical factor, but future, more extensive studies are required.
