Changes of the Meibomian Gland According to Age in the Normal Korean Population.
10.3341/jkos.2015.56.1.13
- Author:
Joo Hyun KIM
1
;
Jin Woo RO
;
Kayoung YI
;
Dong Gyu CHOI
;
Ha Kyoung KIM
;
Joon Young HYON
;
Won Ryang WEE
;
Young Joo SHIN
Author Information
1. Department of Ophthalmology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea. schinn@hanmail.net
- Publication Type:Original Article
- Keywords:
Meibomian gland;
Meibomography;
Meiboscore
- MeSH:
Adult;
Aging;
Eyelids;
Female;
Humans;
Male;
Meibomian Glands*;
Prevalence
- From:Journal of the Korean Ophthalmological Society
2015;56(1):13-18
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To examine the changes in meibomian glands associated with aging in a normal Korean population and to estimate the differences between the upper and lower eyelid in each age group. METHODS: We performed meibography on adult subjects using an infrared charge-coupled device (CCD) camera. Each eyelid was scored based on the loss of meibomian glands, and the meiboscores of the upper and lower eyelids were summed to obtain a score for each eye. Meiboscores were evaluated according to age, sex, and upper and lower eyelid meiboscores in each age group. RESULTS: One hundred seventeen eyes of 117 people were enrolled in this study. The study subjects had an average age of 50.4 +/- 19.1 years (range, 20-92; male, 56; female, 61). There was a significant positive correlation between age and total meiboscore, upper and lower eyelid meiboscore (r = 0.578, p < 0.001; r = 0.550, p < 0.001; r = 0.524, p < 0.001). There were no significant differences in the meiboscores of the upper and lower eyelids in any age group, though meiboscores were significantly higher since 40 year-old group than 20 year-old group (p < 0.001, p < 0.001, p < 0.001, p < 0.001). CONCLUSIONS: Based on noncontact meibography in normal adult eyes, the authors concluded that prevalence of changes in the meibomian glands was about 60% and changes in meibomian glands increase with age.
