Mutagenic effects of Fuji-One and monitor in mice
- Author:
Phan Duc Tran
- Publication Type:Journal Article
- Keywords:
mutagenesis
- MeSH:
Mutagenesis;
Chromosomal Instability
- From:Journal of Practical Medicine
2002;435(11):23-27
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Nowdays in Vietnam, Fuji-One and Monitor are organophosphorus pesticides widely used in agriculture. In order to investigate chromosomal mutagenic effects of Fuji-One and Monitor, we have carried out this study in mice. 4 group of mice were analyzed: Negative control group: 16 male mice were non-exposed to pesticides. Positive control group: 15 male mice were injected into the peritoneum with cyclophosphamide, which is a kind of mutagen. Fuji-One group: 5 male mice were injected into the peritoneum with Monitor. Analyzing of frequencies of chromosomal aberration in bone marrow cells and testicular cells of mice, we found that: (1) Monitor can cause chromosomal mutagenic effects in the bone marrow cells. (2) Fuji-One can cause chromosomal structural and numerical aberration. (3) The rate of chromosomal aberration in Fuji-One group was lower than those in positive control group but they were higher than those in monitor group
