A Case of Cutaneous Alternariosis in Liver Transplant Patient.
- Author:
Jae Yong CHANG
1
;
Ju Hee LEE
;
Kwang Hoon LEE
Author Information
1. Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea. kwanglee@yumc.yonsei.ac.kr
- Publication Type:Case Report
- Keywords:
Cutaneous alternariosis;
Immunosuppression;
Liver transplantation
- MeSH:
Agar;
Alternaria;
Alternariosis*;
Amylases;
Biopsy;
Chloramphenicol;
Female;
Follow-Up Studies;
Humans;
Hyphae;
Immunosuppression;
Inflammation;
Knee;
Liver Transplantation;
Liver*;
Methenamine;
Middle Aged;
Recurrence;
Spores, Fungal
- From:Korean Journal of Medical Mycology
2006;11(3):159-162
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A case of cutaneous alternariosis is reported in a 61-year-old female who underwent liver transplantation one year earlier. The infection manifested as a crusted papule about 1 cm in diameter on the right knee. Histological examination with silver methenamine and periodic acid-Schiff diastase revealed fungal spores and hyphae with chronic granulomatous inflammation. Biopsy fragments inoculated on Sabouraud-glucose agar with chloramphenicol produced colonies which were identified as Alternaria species on the basis of macroscopic and microscopic characters. Complete excision and treatment with 250 mg/day oral terbinafine for one month resulted in a satisfactory course with no signs of local recurrence over follow-up period of one year.
