Cardiac Magnetic Resonance Scar Imaging for Sudden Cardiac Death Risk Stratification in Patients with Non-Ischemic Cardiomyopathy.
10.3348/kjr.2015.16.4.683
- Author:
Eun Kyoung KIM
1
;
Pairoj CHATTRANUKULCHAI
;
Igor KLEM
Author Information
1. Division of Cardiology, Department of Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea.
- Publication Type:Review
- Keywords:
Non-ischemic cardiomyopathy;
Sudden cardiac death;
Cardiac magnetic resonance
- MeSH:
Arrhythmias, Cardiac/*diagnosis;
Cardiomyopathies/*diagnosis;
Cicatrix/*diagnosis;
Death, Sudden, Cardiac;
Defibrillators, Implantable;
Female;
Humans;
Magnetic Resonance Imaging, Cine/*methods;
Myocardium/pathology;
Risk Assessment;
Risk Factors
- From:Korean Journal of Radiology
2015;16(4):683-695
- CountryRepublic of Korea
- Language:English
-
Abstract:
In patients with non-ischemic cardiomyopathy (NICM), risk stratification for sudden cardiac death (SCD) and selection of patients who would benefit from prophylactic implantable cardioverter-defibrillators remains challenging. We aim to discuss the evidence of cardiac magnetic resonance (CMR)-derived myocardial scar for the prediction of adverse cardiovascular outcomes in NICM. From the 15 studies analyzed, with a total of 2747 patients, the average prevalence of myocardial scar was 41%. In patients with myocardial scar, the risk for adverse cardiac events was more than 3-fold higher, and risk for arrhythmic events 5-fold higher, as compared to patients without scar. Based on the available observational, single center studies, CMR scar assessment may be a promising new tool for SCD risk stratification, which merits further investigation.