The anti-parasitic efficacy of ivermectin and pyrantel pamoate compound against canine Toxocara canis and Trichuris vulpis.
- Author:
Heejeong YOUN
1
;
Jeong Chan RA
;
Byung Ki KIM
;
Bokyoung BAE
;
Yong Suk LIM
;
Kyong Hee KIM
;
Kyong Eun LEE
Author Information
1. Department of Veterinary Parasitology, College of Veterinary Medicine, Seoul National University, Seoul 151-742, Korea. younhj@snu.ac.kr
- Publication Type:Original Article
- Keywords:
ivermectin;
ivermectin and pyrantel pamoate compound;
pyrantel pamoate;
Toxocara canis;
Trichuris vulpis
- MeSH:
Animals;
Dogs;
Intestine, Large;
Intestine, Small;
Ivermectin;
Parasites;
Pyrantel;
Pyrantel Pamoate;
Toxocara;
Toxocara canis;
Trichuris
- From:Korean Journal of Veterinary Research
2011;51(4):289-295
- CountryRepublic of Korea
- Language:English
-
Abstract:
Toxocara (T.) canis and Trichuris (T.) vulpis are very important canine parasitic nematodes. T. canis parasitize in small intestine and T. vulpis parasitize in large intestine. In order to control of these nematodes, ivermectin and pyrantel pamoate compound was applied to the dogs infected with these parasites naturally and artificially. This drug was composed of 68.0 microg of ivermectin and 57.0 mg of pyrantel pamoate for small animal, 136.0 microg of ivermectin and 114.0 mg of pyrantel pamoate for middle animal, and 272.0 microg of ivermectin and 227.0 mg of pyrantel pamoate for large animal. Ivermectin in this drug is activity to nematodes and ectoparisites. Pyrantel pamoate in this drug is also activity to nematodes. In this experiment, this drug had a good efficacy against T. canis and T. vulpis in the infected dogs.