Chronic Inflammatory Demyelinating Polyneuropathy Combined With Limited Cutaneous Systemic Sclerosis.
- Author:
Eun Kyung LEE
1
;
Dong Joo YUN
;
Youngchai KO
;
Sang Hyun JANG
;
Soo Jin YOON
;
Gun Sei OH
;
Soo Joo LEE
;
Sung Hye PARK
Author Information
1. Department of Neurology, Eulji University School of Medicine, Daejeon, Korea. djy@eulji.ac.kr
- Publication Type:Case Report
- Keywords:
Chronic inflammatory demyelinating polyneuropathy;
Systemic sclerosis;
Autoimmunity
- MeSH:
Aged;
Autoimmunity;
Biopsy;
Demyelinating Diseases;
Extremities;
Female;
Humans;
Neural Conduction;
Polyneuropathies*;
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating;
Scleroderma, Systemic*;
Sural Nerve
- From:Journal of the Korean Neurological Association
2014;32(1):26-29
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Chronic inflammatory demyelinating polyneuropathy (CIDP) has been rarely reported in systemic sclerosis (SSc). We describe the clinical, electrophysiological, and pathologic findings in a 73-year-old female with established limited cutaneous SSc who later developed CIDP. The patient had progressive limb weakness, sensory loss, and slow nerve conduction velocities. Sural nerve biopsy showed evidence of demyelination and remyelination. This case demonstrates that chronic demyelinating polyneuropathy can be an unusual manifestation of SSc, presumably resulting from an immune-mediated process.
