A case report of malignant paraganglioma with hepatic metastases.
- Author:
Sung Gon JUN
1
;
Yon Joo HA
;
Min Ho KIM
;
Jae Kwang SHIM
;
Yeung Jae KO
;
Dong Jin CHOI
;
Yoon Shig YANG
Author Information
1. Department of Internal Medicine, Pusan Medical Center, Pusan, Korea. docjun@netsgo.com
- Publication Type:Case Report
- Keywords:
Paraganglioma;
Liver;
Neoplasm;
Metastasis
- MeSH:
Abdomen;
Aged;
Biopsy, Needle;
Diagnosis;
Drug Therapy;
Female;
Follow-Up Studies;
Humans;
Liver;
Neoplasm Metastasis*;
Paraganglioma*;
Radiotherapy
- From:Korean Journal of Medicine
2001;61(2):201-205
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of malignant paraganglioma with hepatic metastases. A 70-year old woman developed huge hepatic tumor 2years after complete resection of the retroperitoneal paraganglioma. CT imaging of abdomen revealed huge hepatic masses, which had not been found previously. A needle biopsy on the liver was performed, resulting in a diagnosis of malignant paraganglioma. These tumors are usually benign but can occasionally produce local and distant metastases. Development of metastatic localizations is the only formal proof of malignancy as histology cannot distinguish between benign and malignant paragangliomas. Surgery is the basis of treament and should be performed early in the operable course. Both chemotherapy and radiotherapy could be given, but satisfactory outcomes were not obtained. We suggest that close investigations for metastasis in patient with paraganglioma, seemed benign initially, as well as periodic follow up examinations should be emphasized.
