Lethal Measles Pneumonia after Allogenic Hematopoietic Stem Cell Transplantation.
- Author:
Chang Nyol PAIK
1
;
Dong Gun LEE
;
Hyun Wha JUNG
;
Jung Hyun CHOI
;
Yu Kyung CHO
;
Hoon Jun PARK
;
Seung Hoon LEE
;
Yoon Hee PARK
;
Kyo Young LEE
;
Wan Sik SHIN
;
Woo Sung MIN
;
Chun Choo KIM
Author Information
1. Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Pneumonia;
Measles;
Bone marrow transplantation
- MeSH:
Adult;
Anti-Bacterial Agents;
Autopsy;
Bone Marrow;
Bone Marrow Transplantation;
Child;
Female;
Giant Cells;
Hematopoietic Stem Cell Transplantation*;
Hematopoietic Stem Cells*;
Humans;
Immunocompromised Host;
Immunoglobulins;
Lung;
Lung Diseases, Interstitial;
Measles*;
Pneumonia*;
Respiratory Insufficiency;
Young Adult
- From:Korean Journal of Infectious Diseases
2001;33(4):305-309
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
As a result of the enlarging pool of unvaccinated children and young adults, there has been an increase in measles in our countries. In these situation, it has been reported that measles associated pneumoinia is easily complicated with fatal respiratory failure, especially in immunocompromised patients. Herein we report the case of lethal measles pneumonia after allogenic hematopoietic stem cell transplantation in adults proven by autopsy. Recently, one case of measles was encountered in a 39-year-old female patients after allogenic bone marrow transplanted case (chronic myelogenous leukemia), who progressed into interstitial pneumonia pattern, despite treatment including antibiotics, immunoglobulin. The patient died of giant cell pneumonia compatible with that of measles which was comfirmed in the section of necropsy lung specimen.
