Abdominal Fibromatosis in a Young Child: A Case Study and Review of the Literature.
- Author:
Hyun Hee CHU
1
;
Pyoung Han HWANG
;
Yeon Jun JEONG
;
Myoung Ja CHUNG
Author Information
1. Department of Pathology, Chonbuk National University Medical School, Jeonju, Korea. mjchung@jbnu.ac.kr
- Publication Type:Case Report
- Keywords:
Fibromatosis;
Abdominal wall;
Child
- MeSH:
Abdominal Wall;
beta Catenin;
Child*;
Collagen;
Female;
Fibroblasts;
Fibroma;
Fibromatosis, Abdominal*;
Humans;
Infant;
Necrosis;
Pregnancy;
Vimentin
- From:Korean Journal of Pathology
2013;47(5):472-476
- CountryRepublic of Korea
- Language:English
-
Abstract:
Fibromatoses comprise many different entities of well-differentiated fibroblastic proliferation with variable collagen production and form a firm nodular mass. Abdominal fibromatosis is distinguishable from other forms of fibromatosis because of its location and its tendency to occur in women of childbearing age during or following pregnancy. Abdominal fibromatosis in children is an extremely rare condition. A 15-month-old boy presented with an abdominal wall mass that had recently increased in size. Mass excision was perfomed. The tumor was 4.3x4.1 cm and partly circumscribed. Histologically, the tumor was composed of parallel long fascicles of spindle-cells with a uniform appearance. The edges of the resected mass were infiltrative, and the surgical margins were positive. Mitotic figures were <1/10 high power fields. No cellular atypia or necrosis was present. The tumor cells were positive for vimentin and nuclear beta-catenin staining.
