A Case of Median Raphe Cyst on the Scrotum with Atypical Histologic Features.
- Author:
Jin Young JUNG
1
;
Do Young KIM
;
Chang Ook PARK
;
Hye Jin CHUNG
;
Min Geol LEE
Author Information
1. Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea. mglee@yumc.yonsei.ac.kr
- Publication Type:Case Report
- Keywords:
Dermoid cyst;
Fusion of ectoderm and endoderm;
Immunohistochemical study;
Median raphe cyst;
Mucous cyst
- MeSH:
Anal Canal;
Child;
Decapitation;
Dermoid Cyst;
Ectoderm;
Endoderm;
Epithelium;
Genitalia, Male;
Humans;
Male;
Penis;
Scrotum*;
Urethra
- From:Korean Journal of Dermatology
2006;44(9):1109-1113
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Median raphe cyst is an uncommon condition occuring on the ventral median raphe from the glans penis to the anus and represents a defect in the embryologic development of the male genitalia. The cyst wall may derive from endoderm, ectoderm, or mucous glands which are a normal constitute of the male urethra. It is classified as either a dermoid cyst lined by stratified squamous epithelium of ectodermal origin or a mucous cyst lined by cuboidal or columnar epithelium of endodermal origin. Surgical excision is the treatment of choice. We report a case of an 11-year old boy with three median raphe cysts of the scrotum. The epithelial lining of the cysts was mainly composed of pseudostratified columnar cells with decapitation secretion and focally showed stratified squamous cells and a transitional zone of two types of cells. Immunohistochemically, pseudostratified columnar cells showed CK 7 and CK 13 positivity, but were negative for CK 20. Besides, stratified squamous cells were negative for CK 7, CK 13 and CK 20. We report a rare case of median raphe cyst that is a combined type of dermoid cyst and mucous cyst.
