Invasive Micropapillary Carcinoma of the Breast: Mammographic, Sonographic and MR Imaging Findings.
10.13104/jksmrm.2012.16.3.205
- Author:
Sun Jung RHEE
1
;
Boo Kyung HAN
;
Eun Young KO
;
Jung Hee SHIN
Author Information
1. Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. bkhan@skku.edu
- Publication Type:Original Article
- Keywords:
Breast;
Carcinoma;
Invasive micropapillary carcinoma;
MR imaging;
Sonography
- MeSH:
Breast;
Female;
Humans;
Lymph Nodes;
Mammography;
Neoplasm Metastasis;
Retrospective Studies;
Ultrasonography, Mammary
- From:Journal of the Korean Society of Magnetic Resonance in Medicine
2012;16(3):205-216
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: We performed this study to investigate the characteristic imaging and clinicopathologic features of invasive micropapillary carcinoma of the breast. MATERIALS AND METHODS: Among the 47 women with surgically confirmed invasive micropapillary carcinoma between 2005 and 2009, 32 patients (mean age, 50 years; range, 37-69 years) had all preoperative mammography, ultrasound (US) and MR images. Two radiologists retrospectively assessed the imaging findings, clinical presentation and histological results of the patients. RESULTS: On mammography, 29 of 32 patients had suspicious findings. Among them, a mass (or focal asymmetry) with calcifications was the most common findings (15/32, 65%). The calcifications were noted in 20 patients (63%) and the shape of calcifications was frequently amorphous or punctate (n = 12, 60%). On US and MR imaging, all lesions had suspicious findings. The most common US findings were single (n = 20) or multiple (n = 10) irregular hypoechoic mass (es). The mass was frequently hypoechoic (n = 29, 97%). On MR imaging, the type of lesions was a mass or masses in 23 (72%), a mass combined with non-mass in six patients, and non-mass lesions in three patients. Histologically, axillary lymph nodes metastasis were very common (25/32, 78%). Asymptomatic clinical presentation was not usual (9/32, 28%). CONCLUSION: The imaging features of invasive micropapillary carcinomas strongly suggest malignancy. Microcalcifications on mammography, marked hypoechogenicity on US and an irregular mass, often combined with non-mass on MR are common. Axillary lymph node metastasis is commonly associated.
