Comparative study of radiologic-pathologic findings of experimental clonorchiasis in rabbits.
10.3348/jkrs.1993.29.1.1
- Author:
Kyung Nam RYU
;
Jae Hoon LIM
;
You Jung CHO
;
Moon Ho YANG
- Publication Type:Comparative Study ; Original Article
- MeSH:
Bile Ducts;
Biliary Tract Diseases;
Cholangiography;
Clonorchiasis*;
Clonorchis sinensis;
Dilatation;
Fibrosis;
Humans;
Hyperplasia;
Liver;
Methods;
Rabbits*;
Trematoda;
Ultrasonography
- From:Journal of the Korean Radiological Society
1993;29(1):1-8
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Radiological investigation in patients with clonorchiasis is very important as this is the only method of evaluating the severity of clonorchiasis. In order to correlate the radiologic and pathologic findings of clonorchiasis, fourteen rabbits infested with Clonorchis sinensis and five control rabbits were examined radiologically by ultrasonography, computed tomography and cholangiography and the results were correlated with pathologic findings. Dilatation of the intrahepatic small bile ducts of the liver was due to obstruction by flukes: oval or elliptical small filling defects or irregular margin of the bile ducts on cholangiogram or intraluminal echoes on sonogram represented flukes per se; periductal thickening on sonogram and periductal enhancement of bile ducts on CT were due to inflammatory cell infiltration, adenomatous hyperplasia and periductal fibrosis: band like enhancement at the periphery of the liver on CT represented proliferated bile ducts, destruction of liver cells and resultant fibrosis. The study confirmed the pathological bases for the radiological findings of clonorchiasis in liver and bile ducts and will, perhaps, serve as a basis for the future radiologic-pathological correlation of clonorchiasis and in further clinical and experimental researches in the biliary tract diseases.
