Clinical and Pathologic Findings of Dysplastic Nevus: Review of 15 Cases.
- Author:
Sang Boo SHIN
1
;
Dong Won LEE
;
Jun Young LEE
;
Baik Kee CHO
Author Information
1. Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Dysplastic nevus;
Incidence;
Clinical finding;
Pathologic finding
- MeSH:
Biopsy;
Dysplastic Nevus Syndrome*;
Eosinophils;
Female;
Humans;
Hyperplasia;
Incidence;
Korea;
Male;
Mitosis;
Nevus, Pigmented;
Shoulder
- From:Korean Journal of Dermatology
2000;38(8):1055-1062
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: The dysplastic nevus is a rare form of melanocytic nevus, but the clinical criteria and histopathologic finding are still debated. There are no studies of dysplastic nevus in korea except a few case reports. OBJECTIVE: This study was aimed to evaluate the clinical and histopathological characteristics of dysplastic nevus developed in korean. METHODS: We reviewed the clinical and histopathologic finding of 15 patients diagnosed as dysplastic nevus on the biopsy. RESULTS: The result were as follows ; 1. The incidence of dysplastic nevus in our study was 9.9 cases/100,000 population 2. The subjects consisted of 9 males and 6 females. 3. The common onset of age was 11-20. 4. The common site of dysplastic nevus was the trunk. 5. The common pattern of lesional change was asymmetry and color variegation. 6. The common clinical findings of the dysplastic nevus was multiple, 5-12mm size, multipapular surface, ill-demarcated margin and brown/black color. 7. The pathologic findings including shoulder phenomenon, melanocytic nest, patchy lymphohistiocytic infiltration, melanophage, scattered atypical epitheloid cell, random atypia, anisokaryosis and no mitosis was shown in all the patients, but eosinophilic hyperplasia was shown in 13 patients. 8. The mild atypia in the Duke grading system was the most common. There was significant positive correlation between architectural and cytologic scores(Pearson correlation test, P<0.05, r=0.97). CONCLUSION: Although the incidence of the dysplastic nevus in our study was much lower than that of the west, the clinicopathologic findings were not different.
