A Case of Pulmonary Epithelioid Hemangioendothelioma.
10.4046/trd.1999.47.5.691
- Author:
Kwan Yeung KIM
1
;
Chang Ho KIM
;
Ji Wung SOHN
;
Seung Ick CHA
;
Sang Chul CHAE
;
Jae Yong PARK
;
Tae Hoon JUNG
;
Tae In PARK
;
Keun Yeung KWON
Author Information
1. Department of Internal Medicine, College of Medicine, Kyungpook National University, Korea.
- Publication Type:Case Report
- Keywords:
Epithelioid hemangioendothelioma;
Lung
- MeSH:
Adult;
Biopsy;
Blood Vessels;
Female;
Hemangioendothelioma, Epithelioid*;
Humans;
Hyalin;
Lung;
Mass Screening;
Needles;
Radiography, Thoracic;
Thorax;
Tomography, X-Ray Computed;
Vacuoles;
von Willebrand Factor;
X-Ray Film
- From:Tuberculosis and Respiratory Diseases
1999;47(5):691-696
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Epithelioid hemangioendothelioma (EH) is a rate pulmonary vascular malignancy. Clinically, EH has been considered as an indolent, generally non-aggressive tumor. We report a case of EH which was confirmed by open lung biopsy. A 34-year-old woman was admitted for further evaluation of multiple small (less than 2cm in size) nodules, incidentally detected on screening chest radiograph. The chest CT showed multiple, relatively well-marginated, variable sized nodules at both whole lung. Transbronchial lung biopsy and transthoracic needle aspiration were nondiagnostic and open lung biopsy was performed from right middle lobe of lung. On light-microscopic examination, the nodules were composed of a poorly cellular hyaline core and a more cellular peripheral zone which extended into air space in a micropolypoid fashion and obliterated blood vessels. The tumor cells at the peripheral zone had intracytoplasmic vacuoles which suggested primitive, vascular differentiation. Immuno-histochemical study revealed the cellular area which gave positive reaction to factor VIII-related antigen. She received no specific therapy after open lung biopsy and chest X-ray films had showed no change for about two years.
