The Measurement of Plasma B-Endorphin in Acute Carbon Monoxide Poisoning.
- Author:
Won Tsen KIM
1
;
Kyung Gyu CHOI
;
Myung Sik LEE
;
Il Saing CHOI
;
Jin Soo KIM
Author Information
1. Department of Internal medicine, Wonju Medical college, Yonsei University.
- Publication Type:Original Article
- MeSH:
Acidosis;
Anoxia;
Brain;
Brain Ischemia;
Carbon Monoxide Poisoning*;
Carbon Monoxide*;
Carbon*;
Plasma*;
Poisoning
- From:Journal of the Korean Neurological Association
1988;6(2):176-179
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Pathophysiology of acute carbon monoxide poisoning is not clear. It is generally accepted that hypoxic and/or anoxic insult is very significant role in the pathophysiology of acute acrbon monoxide poisoning, but many arguments are documented especially focal hypoxia or metabalic acidosis within brain parenchyme. In sofar such a focal change seems to be largely depend upon focal change of neuroendocrine substances including B-endorphin. Also B-endorphin is known to be responsble to the pathogenesis of cerebral ischemia. Though the possible relationship between the alteration of level of B-endorphin and hypoxia, it is seldom to pay attention to the role of B-endorphin in carbon monoxide intoxication. We measured plasma B-endorphin in acute carbon monoxide intoxication and compared with the value of control group. There was no difference between control group and acute carbon monoxide poisoning group, the possible role of B-endorphin in acute carbon monoxide poisoning should not be excluded. We suggest the more comprehensive and newly programmed study seems to need for clarifying the possible role of B-endorphin in acute carbon monoxide poisoning.
