A Case of Antenatally Detected Schizencephaly.
- Author:
Bong Jin JEONG
1
;
Kee Su LEE
;
Eui Jung CHOONG
;
Jin Seok HWANG
;
Young Hywan KIM
Author Information
1. Department of Obstetrics and Gynecology, Dong-Gang Hospital, Ulsan, Korea.
- Publication Type:Case Report
- Keywords:
Schizencephaly;
Antenatal diagnosis
- MeSH:
Blindness;
Brain;
Female;
Humans;
Intellectual Disability;
Lateral Ventricles;
Malformations of Cortical Development*;
Muscle Spasticity;
Neurons;
Pregnancy;
Pregnancy Trimester, Third;
Prenatal Diagnosis;
Seizures
- From:Korean Journal of Obstetrics and Gynecology
2002;45(3):529-532
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Schizencephaly is an unusual condition rarely detected antenatally. It is a neuronal migrational disorder consisting of clefts in the brain that communicate with the lateral ventricles. The etiology and the pathogenesis is not clearly estabilished. While some authors advocate a vascular insult with a secondary effect on brain development, others suggest a primary cerebral dysgenesis by genetic or acquired factors. The importance of making an accurate antenatal diagnosis is that the outcome for schizencephaly in considerably poor than for other causes of ventriculomegaly. Typical symtoms include seizures, mental retardation, spastic tetraplagia and blindness. We report a case of typeIIschizencephaly that was diagnosed antenatally in the third trimester with a brief reiew of literatures.
