Analysis of Clinical Features and Prognostic Factor Analysis of Orbital and Adnexal Lymphoma.
10.3341/jkos.2013.54.1.12
- Author:
Sang Jun LEE
1
;
Jae Ho JUNG
;
Hee Young CHOI
Author Information
1. Department of Ophthalmology, Pusan National University School of Medicine, Busan, Korea. hychoi@pusan.ac.kr
- Publication Type:Original Article
- Keywords:
Chemotherapy;
Lymphoma;
Orbit;
Prognosis;
Radiotherapy
- MeSH:
Conjunctiva;
Drug Therapy;
Dry Eye Syndromes;
Factor Analysis, Statistical*;
Female;
Humans;
Lymphoid Tissue;
Lymphoma*;
Lymphoma, B-Cell, Marginal Zone;
Male;
Medical Records;
Orbit*;
Prognosis;
Radiotherapy;
Retrospective Studies
- From:Journal of the Korean Ophthalmological Society
2013;54(1):12-18
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To study the clinical features, pathophysiologic and radiologic characteristics, and prognostic factors in patients with orbital and adnexal lymphoma. METHODS: The medical records of patients who were diagnosed with orbital and adnexal lymphoma, and patients who were treated and observed, were retrospectively reviewed. Information regarding age, sex, initial symptoms and signs when visiting the hospital, mass location and features, histology and staging, response to treatment and side effects, and prognosis were collected. RESULTS: Fifty-four patients, with an equal number of men and women, were diagnosed with orbital and adnexal lymphoma. The average age was 50.9 years (14 to 82 years). The main symptom was orbital swelling, and the main site was conjunctiva. Histologically, Mucosa-Associated Lymphoid Tissue (MALT) lymphoma was the most observed. The major ocular complication was dry eye syndrome, which showed good response with ophthalmic treatment. Radiologic features did not have prognostic relevance. CONCLUSIONS: Most orbital and adnexal lymphomas were MALT lymphomas. Proper therapy according to stage can result in a good response and remission. In the present study, the therapy complications were well-controlled with medical treatment, and radiologic features of a mass could not be considered as a prognostic factor.
