A Study of Subclinical Thyroid Function Disorder and the Risk of Coronary Artery Disease in Women.
- Author:
Soon Gyo YEOUM
1
;
Chai Soon PARK
Author Information
1. Department of Nursing, Seoil University, Korea.
- Publication Type:Original Article
- Keywords:
Thyroid hormone;
Coronary artery disease
- MeSH:
Blood Pressure;
Coronary Artery Disease;
Coronary Vessels;
Female;
Humans;
Hyperthyroidism;
Hypothyroidism;
Incidence;
Logistic Models;
Risk Factors;
Smoke;
Smoking;
Thyroid Gland;
Thyroid Hormones
- From:Journal of Korean Academy of Adult Nursing
2010;22(1):80-89
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: This paper has attempted to investigate the association between the subclinical thyroid function disorder caused by natural change in thyroid hormones or thyroid remedies and the incidence of CHD. METHODS: Data was analyzed of 7,675 women who had undergone health examinations in a hospital in Gyeonggi-do between January 2007 and December 2008. The covariation of the coronary risk factors such as age, BMI, HbA1C, systolic blood pressure, LDL:HDL-cholesterol ratio, CRP, smoking and exercise were analyzed by using logistic regression analysis. RESULTS: A significant increase in serum TSH was observed with higher age (F=26.91, p=.00). In terms of age, the risk of CHD started to gradually increase since the 40s and sharply since the 60s (chi-square=113.29, p=.00). The serum TSH was the most significant parameter influencing CHD (B=.12, p=.00). The risk of coronary artery disease was 3.12 times higher in the subclinical hypothyroidism group (OR=3.12) while no significant difference was observed in the subclinical hyperthyroidism group. CONCLUSION: Subclinical hypothyroidism may be an independent risk factors for CHD. A nurse nursing patients with thyroid disorder should be well informed of their state of subclinical thyroid function disorder and make efforts to extend their health expectancy.
