Long-Term Prognosis of Patients with an Implantable Cardioverter-Defibrillator in Korea.
10.3349/ymj.2017.58.3.514
- Author:
Jae Sun UHM
1
;
Tae Hoon KIM
;
In Cheol KIM
;
Young Ah PARK
;
Dong Geum SHIN
;
Yeong Min LIM
;
Hee Tae YU
;
Pil Sung YANG
;
Hui Nam PAK
;
Seok Min KANG
;
Moon Hyoung LEE
;
Boyoung JOUNG
Author Information
1. Division of Cardiology, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. cby6908@yuhs.ac
- Publication Type:Original Article
- Keywords:
Heart failure;
implantable cardioverter-defibrillator;
primary prevention;
sudden cardiac death
- MeSH:
Death, Sudden, Cardiac;
Defibrillators, Implantable*;
Follow-Up Studies;
Heart Failure;
Humans;
Korea*;
Primary Prevention;
Prognosis*;
Secondary Prevention
- From:Yonsei Medical Journal
2017;58(3):514-520
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: The objective of this study was to elucidate the long-term prognosis of patients with implantable cardioverter-defibrillators (ICDs) in Korea. MATERIALS AND METHODS: We enrolled 405 patients (age, 57.7±16.7 years; 311 men) who had undergone ICD implantation. The patients were divided into three groups: heart failure (HF) and ICD for primary (group 1, n=118) and secondary prevention (group 2, n=93) and non-HF (group 3, n=194). We compared appropriate and inappropriate ICD therapy delivery among the groups and between high- (heart rate ≥200 /min) and low-rate (<200 /min) ICD therapy zones. RESULTS: During the follow-up period (58.9±49.8 months), the annual appropriate ICD therapy rate was higher in group 2 (10.4%) than in groups 1 and 3 (6.1% and 5.9%, respectively, p<0.001). There were no significant differences in annual inappropriate ICD therapy rate among the three groups. In group 1, the annual appropriate ICD therapy rate was significantly lower in patients with a high-rate versus a low-rate therapy zone (4.5% and 9.6%, respectively, p=0.026). In group 3, the annual inappropriate ICD therapy rate was significantly lower in patients with a high-rate versus a low-rate therapy zone (3.1% and 4.0%, respectively, p=0.048). CONCLUSION: Appropriate ICD therapy rates are not low in Korean patients with ICD, relative to prior large-scale studies in Western countries. Appropriate and inappropriate ICD therapy could be reduced by a high-rate therapy zone in patients with HF and ICD for primary prevention, as well as non-HF patients, respectively.
