Comparison of Group A, B and C Rotaviral Gastroenteritis among Children in Korea: Prevalence and Clinical Features.
- Author:
Kil Seong BAE
;
Woo Ri BAE
;
Ji Hoon KIM
;
Joong Hyun BIN
;
Hyun Hee KIM
;
Hee Jin LEE
;
Wonbae LEE
- Publication Type:Original Article
- Keywords:
Rotavirus;
Gastroenteritis;
Prevalence
- MeSH:
Child*;
Diarrhea;
DNA;
Gastroenteritis*;
Gyeonggi-do;
Humans;
Infant;
Korea;
Polymerase Chain Reaction;
Prevalence*;
Rotavirus;
Rotavirus Infections;
Vomiting
- From:Korean Journal of Pediatric Infectious Diseases
2014;21(2):96-103
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: The aim of this study is that the prevalence of rotavirus infection was evaluated by each group and clinical features of group A, B and C rotaviruses infections were described respectively to compare one with another. METHODS: Between January 2010 and December 2010, we enrolled a group of children below 10 years of age admitted for management of acute diarrhea at the Catholic University of Korea Bucheon St. Mary's Hospital. A total of 310 stool samples documented to be free of common bacterial pathogens were collected from children with diarrhea. The presence of group A, B or C rotavirus is indicated by amplification of DNA segments of the expected lengths after the first and second PCRs. RESULTS: In a total of 310 stool specimens, 40 (12.9%) specimens were positive for rotaviruses. These included 23 (7.4%) positive for group A, 5 (1.6%) for group B and 12 (3.9%) for group C rotaviruses. Group B rotavirus infected patients had significantly less diarrheas per day (group A: P=0.01, group C: P=0.01) and shorter duration of vomiting days (group A: P=0.03, group C: P=0.03) than those with group A and C rotaviruses infection respectively. All the group B rotaviruses had been isolated in March and October. Group C rotavirus infections were prevalent during late summer and early winter and peaked in October. CONCLUSION: These findings indicate that group B and C rotaviruses are notable causes or the contributing causes of diarrhea among infants and children in Korea.
