Mucosal Schwann-Cell Hamartoma Diagnosed by Using an Endoscopic Snare Polypectomy.

Author: Myoung Nam BAE ¹ ; Jung Eun LEE ; Sang Mook BAE ; Eun Young KIM ; Eun Ok KIM ; Sung Hoon JUNG ; Jung Hwan OH ; Ki Ok MIN
Author Information

1. Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. shjung74@catholic.ac.kr
Publication Type:Case Report
Keywords: Schwann cells; Hamartoma; Neurofibroma; Neuroma; Colon polyps
MeSH: Colon; Hamartoma; Mesoderm; Mucous Membrane; Neurofibroma; Neurofibromatoses; Neuroma; Polyps; S100 Proteins; Schwann Cells; SNARE Proteins
From:Annals of Coloproctology 2013;29(3):130-134
CountryRepublic of Korea
Language:English
Abstract: Colorectal polyps of mesenchymal origin are a rare group of colorectal disorders. A "mucosal Schwann-cell hamartoma," which is one type of polypoid lesion that originates from the mesenchyme, is a newly-proposed disease entity to be distinguished from the neurofibromas found in type-1 neurofibromatosis. This lesion is composed of pure Schwann-cell proliferation in the lamina propria and shows diffuse immunoreactivity for the S-100 protein. We report a case of a polypoid lesion of the colon with the features of this recently-proposed disease entity.