EEG Source Imaging in Partial Epilepsy in Comparison with Presurgical Evaluation and Magnetoencephalography.
10.3988/jcn.2015.11.4.319
- Author:
Chae Jung PARK
1
;
Ji Hye SEO
;
Daeyoung KIM
;
Berdakh ABIBULLAEV
;
Hyukchan KWON
;
Yong Ho LEE
;
Min Young KIM
;
Kyung Min AN
;
Kiwoong KIM
;
Jeong Sik KIM
;
Eun Yeon JOO
;
Seung Bong HONG
Author Information
1. Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. sbhong@skku.edu
- Publication Type:Original Article
- Keywords:
partial epilepsy;
EEG source imaging;
MEG source imaging;
source localization;
presurgical evaluation;
epilepsy surgery
- MeSH:
Electrodes;
Electroencephalography*;
Epilepsies, Partial*;
Epilepsy;
Epilepsy, Temporal Lobe;
Humans;
Insulator Elements;
Magnetoencephalography*;
Scalp;
Seizures
- From:Journal of Clinical Neurology
2015;11(4):319-330
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND AND PURPOSE: The aim of this study was to determine the usefulness of three-dimensional (3D) scalp EEG source imaging (ESI) in partial epilepsy in comparison with the results of presurgical evaluation, magnetoencephalography (MEG), and electrocorticography (ECoG). METHODS: The epilepsy syndrome of 27 partial epilepsy patients was determined by presurgical evaluations. EEG recordings were made using 70 scalp electrodes, and the 3D coordinates of the electrodes were digitized. ESI images of individual and averaged spikes were analyzed by Curry software with a boundary element method. MEG and ECoG were performed in 23 and 9 patients, respectively. RESULTS: ESI and MEG source imaging (MSI) results were well concordant with the results of presurgical evaluations (in 96.3% and 100% cases for ESI and MSI, respectively) at the lobar level. However, there were no spikes in the MEG recordings of three patients. The ESI results were well concordant with MSI results in 90.0% of cases. Compared to ECoG, the ESI results tended to be localized deeper than the cortex, whereas the MSI results were generally localized on the cortical surface. ESI was well concordant with ECoG in 8 of 9 (88.9%) cases, and MSI was also well concordant with ECoG in 4 of 5 (80.0%) cases. The EEG single dipoles in one patient with mesial temporal lobe epilepsy were tightly clustered with the averaged dipole when a 3 Hz high-pass filter was used. CONCLUSIONS: The ESI results were well concordant with the results of the presurgical evaluation, MSI, and ECoG. The ESI analysis was found to be useful for localizing the seizure focus and is recommended for the presurgical evaluation of intractable epilepsy patients.
