The meaning of anti-Müllerian hormone levels in patients at a high risk of poor ovarian response.
10.5653/cerm.2016.43.3.139
- Author:
Hyun Jong PARK
1
;
Geun Ho LEE
;
Du Sik GONG
;
Tae Ki YOON
;
Woo Sik LEE
Author Information
1. Department of Obstetrics and Gynecology, CHA Gumi Medical Center, Gumi, Korea.
- Publication Type:Review
- Keywords:
Anti-Müllerian hormone;
Fertilization in vitro;
Infertility;
Pregnancy rate
- MeSH:
Female;
Fertilization in Vitro;
Follicle Stimulating Hormone;
Humans;
Infertility;
Ovarian Reserve;
Pregnancy;
Pregnancy Rate;
Reproductive Techniques, Assisted;
Sensitivity and Specificity
- From:Clinical and Experimental Reproductive Medicine
2016;43(3):139-145
- CountryRepublic of Korea
- Language:English
-
Abstract:
Measurements of ovarian reserve play an important role in predicting the clinical results of assisted reproductive technology (ART). The ideal markers of ovarian reserve for clinical applications should have high specificity in order to determine genuine poor responders. Basal follicle-stimulating hormone levels, antral follicle count, and serum anti-Müllerian hormone (AMH) levels have been suggested as ovarian reserve tests that may fulfill this requirement, with serum AMH levels being the most promising parameter. Serum AMH levels have been suggested to be a predictor of clinical pregnancy in ART for older women, who are at a high risk for decreased ovarian response. We reviewed the prognostic significance of ovarian reserve tests for patients undergoing ART treatment, with a particular focus on the significance of serum AMH levels in patients at a high risk of poor ovarian response.