The Correlation between Relative Renal Uptake of (99m)Tc-DMSA Renal Scan and Glomerular Filtration Rate in Patients with Reduced Renal Function.
- Author:
Seoung Jae AN
1
;
Yoo Suck JUNG
;
Hyun Chul JUNG
;
Soo Bong LEE
;
Ihm Soo KWAK
;
Ha Yeon RHA
Author Information
1. Department of Internal Medicine, College of Medicine, Pusan National University, Busan, Korea. iskwak@hyowon.pusan.ac.kr
- Publication Type:Original Article
- Keywords:
Glomerular filtration rate;
(99m)Tc-DMSA renal scan;
(99m)Tc-DTPA renal scan
- MeSH:
Creatinine;
Filtration;
Glomerular Filtration Rate*;
Humans;
Male
- From:Korean Journal of Nephrology
2002;21(4):602-609
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Glomerular filtration rate(GFR) is an important parameter for the evaluation and monitoring of renal function. The aim of this study was to investigate the correlation between the relative 1 hour uptake of (99m)Tc-DMSA renal scan(DMSA- %uptake, TRUR) and GFR which was estimated by (99m)Tc-DTPA, serum creatinine and 24 hour-urinary creatinine excretion. METHODS: Between January 1998 and March 2001, 65 patients had undergone (99m)Tc-DMSA renal scan, (99m)Tc-DTPA renal scan, serum creatinine and 24 hour-urinary creatinine excretion. Of them, 42 patients had moderately or severely reduced renal function(DTPA-GFR 0.05). In group B, TRUR (mean+/-S.D. 16.3+/-7.4%) was significantly correlated with DTPA-GFR(r=0.731, p < 0.01). In both group, serum creatinine, Ccr and C and G Ccr were significantly correlated with TRUR. CONCLUSION: Although the relative 1 hour uptake of the (99m)Tc-DMSA renal scan, as a method of renal cortical image could not estimate the true GFR, it showed a good correlation with GFR in patients with moderately reduced renal function. (99m)Tc-DMSA renal scan seems to be helpful to evaluate the renal function in patients with moderately reduced renal function.
