A Case Report of Progressive Subcortical Gliosis.
- Author:
Sang Yun KIM
1
;
Duk Lyul LA
;
Seong Ho PARK
;
Hae Soo KOO
;
Je Geun CHI
Author Information
1. Department of Neurology, College of Medicine, Hallym University, Korea.
- Publication Type:Original Article
- MeSH:
Alzheimer Disease;
Biopsy;
Brain;
Dementia;
Gliosis*;
Humans;
Neurofibrillary Tangles;
Neurons;
Pick Disease of the Brain;
Plaque, Amyloid;
Siblings
- From:Journal of the Korean Neurological Association
1995;13(3):696-702
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A patient presenting with the characteristic clinical features of the dementia of Pick's type is described, in whom neuropathological examination of brain biopsy material revealed atypical features, including extensive subcotical gliosis with mild cortical neuronal loss and without any neuronal cytoskeletal inclusions (Pick bodies, neurofibrillary tangles, and Lewy bodies) and amyloid deposits (senile plaques). And she has the suggestive family history of the same clinical features in her two brothers. So, the clinical and pathological features are discussed with particular reference to typical Alzheimer's disease and Pick's disease, and it is proposed that the case should be classified as familial progressive subcortical gliosis.
