Plugging the Biopsy Tract in Rabbit Liver: Gelfoam, Fibrin Sealant and NBCA.
10.3348/jkrs.1998.39.1.137
- Author:
Byung Kook KWAK
1
;
Kul Ho JUNG
;
Chi Hoon CHOI
;
Hye Ran YOON
;
Yong Ok PARK
;
Chang Joon LEE
;
Hee Hon KIM
;
Hee Jin CHANG
;
Hyung Jin SHIM
Author Information
1. Department of Diagnostic Radiology, National Medical Center, Korea.
- Publication Type:Original Article
- Keywords:
Animals, Liver, biopsy;
Biopsies, complications;
Biopsies, technology
- MeSH:
Biopsy*;
Bleeding Time;
Catheters;
Fibrin Tissue Adhesive*;
Fibrin*;
Fibrosis;
Foreign-Body Reaction;
Gelatin Sponge, Absorbable*;
Hemorrhage;
Liver*;
Needles;
Rabbits
- From:Journal of the Korean Radiological Society
1998;39(1):137-142
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To evaluate the effect of plugging the biopsy tract in rabbit liver and the pathologic changes caused by plugging materials. MATERIALS AND METHODS: Thirty-two New Zealand White rabbits were divided into four groups(eight rabbits in each) and compared with one another. They were labeled group A(control), B(gelfoam),C(fibrin sealant) or D(NBCA). The liver was exposed and biopsied with an 18G disposible biopsy gun. The inner Tru-cut needle was withdrawn and plugging was undertaken through the outer cannula of the biopsy gun. Bleeding times of each material were compared. The rabbits were sacrificed and pathologically evaluated for 17 days. RESULTS: Mean bleeding times were 46.7+/-34.5 sec in group A, 42.9+/-54.7 sec in group B, 12.6+/-15.0 sec in group C, and 0 sec in group D. In groups C and D, these results were statistically significant(p<0.01). Pathologically, fibrin sealant was lowest in foreign body reaction and fibrosis. NBCA was effective for the prevention of hemorrhage. CONCLUSION: NBCA and fibrin sealant effectively plug the biopsy tract through the outer cannula of an18 G biopsy gun.
