A Case of Kounis Syndrome Induced by a Non-Steroidal Anti-Inflammatory Drug.
- Author:
Eun Jeong CHOI
1
;
Yun Ho SHIN
;
Dong Kil NA
;
Ji Hyun KIM
;
Seonghoon CHOI
;
Jung Rae CHO
;
Namho LEE
Author Information
1. Department of Internal Medicine, Hallym University College of Medicine, Seoul, Korea. namholee2@hotmail.com
- Publication Type:Case Report
- Keywords:
Anaphylaxis;
Myocardial infarction;
Syndrome
- MeSH:
Allergens;
Anaphylaxis;
Contrast Media;
Coronary Vessels;
Humans;
Hymenoptera;
Hypersensitivity;
Injections, Intramuscular;
Latex;
Myocardial Infarction;
Spasm;
Thrombosis;
Venoms
- From:Korean Journal of Medicine
2012;82(6):724-728
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In 1991, Kounis and Zavras described the "syndrome of allergic angina" as the coincidental occurrence of angina and allergic reactions by inflammatory mediators released during the allergic insult. Presently, both allergic angina and allergic myocardial infarction are referred to as "Kounis syndrome." Several allergens, including drugs, Hymenoptera venom, latex, food, and contrast media have been reported to trigger Kounis syndrome. Three variants of this syndrome have been described. Type I includes patients with normal coronary arteries, Type II includes patients with preexisting atheromatous disease where acute release of inflammatory mediators can induce coronary artery spasms, and Type III is associated with intracoronary thrombus formation caused by an allergic reaction. We report a case of Kounis syndrome who presented as acute myocardial infarction after intramuscular injection of a non-steroidal anti-inflammatory drug.
