Ovarian Squamous Cell Carcinoma Associated with Endometriosis: Poor Response to Chemotherapy.
- Author:
Seob JEON
1
Author Information
1. Department of Obstetrics and Gynecology, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan, Korea. sjeon4595@gmail.com
- Publication Type:Case Report
- Keywords:
Squamous cell carcinoma;
Endometriosis;
Chemotherapy
- MeSH:
Abdomen;
Abdominal Pain;
Adult;
Carboplatin;
Carcinoma, Squamous Cell*;
Cisplatin;
Drug Therapy*;
Drug Therapy, Combination;
Electrons;
Endometriosis*;
Epithelial Cells*;
Female;
Humans;
Liver;
Lymph Nodes;
Neoplasm Metastasis;
Paclitaxel;
Prognosis;
Recurrence;
Tomography, X-Ray Computed
- From:Soonchunhyang Medical Science
2017;23(1):56-60
- CountryRepublic of Korea
- Language:English
-
Abstract:
The occurrence of ovarian squamous cell carcinoma associated with ovarian endometriosis is extremely rare. Several studies revealed poor prognosis for ovarian squamous cell carcinoma especially when associated with endometriosis. We report a case of ovarian squamous cell carcinoma that invades the parametrium that is also associated with ovarian endometriosis. A 41-year-old woman with stage IIB ovarian squamous cell carcinoma was treated with debulking surgery followed by six courses combination chemotherapy composed of paclitaxel and carboplatin. Twenty months after the last course of chemotherapy (3 months after normal positron emission tomography–computed tomography [CT] scanning), upper abdominal pain developed and abdomen CT scan revealed multiple metastasis in liver and paraaortic lymph node. Although two cycles of paclitaxel and cisplatin was administrated, she died of disease three months after the recurrence.