Surgical Resection of Small Cell Lung Cancer ( SCLC ).
- Author:
Kyung Young CHUNG
1
;
Gi Pyo HONG
;
Kil Dong KIM
;
Dae Jun KIM
;
Joo Hang KIM
Author Information
1. Department of Thoracic and Cardiovascular Surgery, Yonsei Unversity College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Carcinoma;
oat cell carconoma;
Lung surgery
- MeSH:
Carcinoma, Squamous Cell;
Drug Therapy;
Female;
Follow-Up Studies;
Hand;
Humans;
Lymph Node Excision;
Lymph Nodes;
Male;
Mastectomy, Segmental;
Mortality;
Neoplasm Metastasis;
Neoplasm Staging;
Pelvic Bones;
Radiotherapy;
Recurrence;
Small Cell Lung Carcinoma*
- From:The Korean Journal of Thoracic and Cardiovascular Surgery
1998;31(12):1195-1199
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Bafckground: Thr role and indication of surgery in the treatment of small cell lung cancer (SCLC) is currently limited and unsettled. MATERIAL AND METHOD: We analyzed the surgical results of 9 patients with SCLC at Yosei Medical Center from January 1990 to December 1996. There were 8 males and 1 female, and their mean age was 57.2 years (range; 35-76). Preoperatively SCLC was confirmed in 5, but the other 4 cases were diagnosed as undifferentiated squamous cell carcinoma. All patients underwent pulmoinary resection (lobectomy;5, lobectomy, segmentectomy and en-bloc resection of rib;1, bilobectomy; 2, pneumonectomy;1) and mediastinal lymph node dissection. RESULTS: There were no operative mortality with two complications (postoperative bleeding;1, arrhythmia;1). All cases were diagnosed as SCLC histologically and their TNM staging were confirmed as follows: T1N0M0;1, T2N0M0;4, T3N0M0;1, T3N1M0;1, T2N2M0; 1, T4N0M0;1. All patients had received postoperative chemotherapy, and radiotherapy was combined in 4 patients. During follow up period (range 1-63 months; mean 33.0months), there was only one metastasis to pelvic bone among 8 patients without lymph node metastasis, and all patients were alive. On the other hand, among 3 patients who had regional and/or mediastinal lymph node metastasis or T4 lesion, all patients had recurrences (local;2, brain;1), and 2 patients died. CONCLUSION: We suggest that the use of TNM staging is beneficial, and surgical resection should be recommended in the patients with early staged SCLC as an important treatment modality.