A Case of Reversible Peripheral Neuropathy Caused by Chronic Phenytoin Intoxication.
- Author:
Young Su HAN
1
;
Jeong Seon CHO
;
Sang Eun PARK
;
Jung Mee KIM
;
Sang Won HA
;
Jeong Ho HAN
;
Eun Kyoung CHO
;
Doo Eung KIM
Author Information
1. Department of Neurology, Seoul Veterans Hospital, Seoul, Korea. han4636@hanmail.net
- Publication Type:Case Report
- Keywords:
Phenytoin;
Reversible peripheral neuropathy;
Intoxication
- MeSH:
Humans;
Middle Aged;
Peripheral Nervous System Diseases*;
Phenytoin*
- From:Journal of Korean Epilepsy Society
2006;10(1):56-59
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Peripheral neuropathy has been uncommon reported as one of neurologic adverse effects associated with phenytoin. A 53 year-old man presented with clinical and electrophysiologic signs of peripheral neuropathy after 13 years of phenytoin administration. Despite a modest dose of phenytoin (300 mg/day), blood level was 40 microg/ml. After discontinuing phenytoin about eight months, the peripheral neuropathy was improved. We present a case of reversible peripheral neuropathy caused by chronic phenytoin intoxication.