Severe Bleeding and Perforation Are Rare Complications of Endoscopic Ultrasound-Guided Fine Needle Aspiration for Pancreatic Masses: An Analysis of 3,090 Patients from 212 Hospitals.
- Author:
Tsuyoshi HAMADA
1
;
Hideo YASUNAGA
;
Yousuke NAKAI
;
Hiroyuki ISAYAMA
;
Hiromasa HORIGUCHI
;
Shinya MATSUDA
;
Kiyohide FUSHIMI
;
Kazuhiko KOIKE
Author Information
1. Department of Gastroenterology, The University of Tokyo Graduate School of Medicine, Tokyo, Japan. isayama-tky@umin.ac.jp
- Publication Type:Original Article ; Evaluation Studies ; Research Support, Non-U.S. Gov't
- Keywords:
Hemorrhage;
Perforation;
Endoscopic ultrasound-guided fine needle aspiration;
Pancreas
- MeSH:
Blood Transfusion/statistics & numerical data;
Endoscopic Ultrasound-Guided Fine Needle Aspiration/*adverse effects;
Female;
Fibrinolytic Agents/adverse effects;
Gastrointestinal Hemorrhage/*etiology;
Humans;
Intestinal Perforation/*etiology;
Male;
Middle Aged;
Pancreatic Neoplasms/*pathology
- From:Gut and Liver
2014;8(2):215-218
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND/AIMS: Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is useful for the pathological diagnosis of pancreatic masses, but patients are susceptible to severe bleeding and perforation. Because the incidence and severity of these complications have not been fully evaluated. METHODS: We aimed to evaluate severe bleeding and perforation after EUS-FNA for pancreatic masses using large-scale data derived from a Japanese nationwide administrative database. RESULTS: In total, 3,090 consecutive patients from 212 low- to high-volume hospitals were analyzed. Severe bleeding requiring transfusion or endoscopic treatment occurred in seven patients (0.23%), and no perforation was observed. No patient mortality was recorded within 30 days of EUS-FNA. The rate of severe bleeding in low-volume hospitals was significantly higher than that in medium- and high-volume hospitals (0.48% vs 0.10%, p=0.045). CONCLUSIONS: Severe bleeding and perforation following EUS-FNA for pancreatic masses are rare, and the procedure is safe.
