Myoclonus as an Anticipatory Symptom of Diffuse Central Nervous System Involvement in Neuropsychiatric Systemic Lupus Erythematosus.
- Author:
Min Jin LEE
1
;
Koeun LEE
;
Jisoo LEE
Author Information
- Publication Type:Case Report
- Keywords: NPSLE; Diffuse neuropsychiatric symptoms; Myoclonus
- MeSH: Abdominal Wall; Adrenal Cortex Hormones; Central Nervous System; Female; Humans; Lupus Erythematosus, Systemic; Lupus Vasculitis, Central Nervous System; Myoclonus; Nervous System; Neurologic Manifestations
- From:Journal of Rheumatic Diseases 2013;20(1):56-58
- CountryRepublic of Korea
- Language:English
- Abstract: The clinical manifestations of nervous system involvement in systemic lupus erythematosus (SLE) are highly diverse and their pathogenic mechanisms are incompletely understood. Neuropsychiatric SLE (NPSLE) poses difficulty in making the proper diagnosis, especially in circumstances where its initial symptoms are diffuse neuropsychiatric symptoms. We describe a 43-year old woman who exhibited a myoclonic jerk of the abdominal wall, followed shortly by acute confusion, which was attributed to SLE. Therapy with high dose corticosteroids completely reversed the symptoms. Myoclonus can be an anticipatory symptom of diffuse neurologic dysfunction in patients with NPSLE.
