- Author:
Ja Young LEE
1
;
You Jeong KIM
;
Ji Hyun LEE
Author Information
- Publication Type:Case Report
- Keywords: Systemic lupus erythematosus; Neuromyelitis optica
- MeSH: Autoimmune Diseases; Brain; Central Nervous System; Demyelinating Diseases; Female; Humans; Lupus Erythematosus, Systemic; Myelitis; Myelitis, Transverse; Neuromyelitis Optica; Optic Nerve; Optic Neuritis; Paraplegia; Sarcoidosis; Spinal Cord
- From:Journal of Rheumatic Diseases 2013;20(1):64-67
- CountryRepublic of Korea
- Language:Korean
- Abstract: Neuromyelitis optica (NMO) is an idiopathic, severe inflammatory demyelinating disease of the central nervous system targeting optic nerves and the spinal cord. It is characterized by acute bilateral visual loss (optic neuritis), acute transverse myelitis, and tends to spare brain early in the disease course. NMO can occur as an isolated condition or secondary to infection, toxin exposure, and autoimmune disease including systemic lupus erythematosus (SLE), sarcoidosis, and Behcet's disease. We experienced a case of SLE with myelitis and recurrent optic neuritis in a 28-year-old woman who presented with recurrent visual disturbance and sudden onset of paraplegia, and report here on this case along with a review of the relevant literature.