Monopolar Radiofrequency Ablation Using a Dual-Switching System and a Separable Clustered Electrode: Evaluation of the In Vivo Efficiency.
10.3348/kjr.2014.15.2.235
- Author:
Jeong Hee YOON
1
;
Jeong Min LEE
;
Eui Jin HWANG
;
In Pyung HWANG
;
Jeehyun BAEK
;
Joon Koo HAN
;
Byung Ihn CHOI
Author Information
1. Department of Radiology, Seoul National University Hospital, Seoul 110-744, Korea. jmsh@snu.ac.kr
- Publication Type:Original Article ; Evaluation Studies ; Research Support, Non-U.S. Gov't
- Keywords:
Liver;
Interventional procedures;
Thermal ablation;
Radiofrequency ablation;
Experimental study
- MeSH:
Animals;
Catheter Ablation/*instrumentation/*methods;
*Electrodes;
Feasibility Studies;
Liver/*surgery;
Male;
Sus scrofa;
Time Factors
- From:Korean Journal of Radiology
2014;15(2):235-244
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: To determine the in vivo efficiency of monopolar radiofrequency ablation (RFA) using a dual-switching (DS) system and a separable clustered (SC) electrode to create coagulation in swine liver. MATERIALS AND METHODS: Thirty-three ablation zones were created in nine pigs using a DS system and an SC electrode in the switching monopolar mode. The pigs were divided into two groups for two experiments: 1) preliminary experiments (n = 3) to identify the optimal inter-electrode distances (IEDs) for dual-switching monopolar (DSM)-RFA, and 2) main experiments (n = 6) to compare the in vivo efficiency of DSM-RFA with that of a single-switching monopolar (SSM)-RFA. RF energy was alternatively applied to one of the three electrodes (SSM-RFA) or concurrently applied to a pair of electrodes (DSM-RFA) for 12 minutes in in vivo porcine livers. The delivered RFA energy and the shapes and dimensions of the coagulation areas were compared between the two groups. RESULTS: No pig died during RFA. The ideal IEDs for creating round or oval coagulation area using the DSM-RFA were 2.0 and 2.5 cm. DSM-RFA allowed more efficient RF energy delivery than SSM-RFA at the given time (23.0 +/- 4.0 kcal vs. 16.92 +/- 2.0 kcal, respectively; p = 0.0005). DSM-RFA created a significantly larger coagulation volume than SSM-RFA (40.4 +/- 16.4 cm3 vs. 20.8 +/- 10.7 cm3; p < 0.001). Both groups showed similar circularity of the ablation zones (p = 0.29). CONCLUSION: Dual-switching monopolar-radiofrequency ablation using an SC electrode is feasible and can create larger ablation zones than SSM-RFA as it allows more RF energy delivery at a given time.
