A Case of Critical Illness Myopathy.
- Author:
Young Dae KIM
1
;
Il Nam SUNWOO
;
Hye Yeon CHOI
;
Sang Don HAN
;
Ha Young SHIN
;
Seung Min KIM
;
Tai Seung KIM
Author Information
1. Department of Neurology, Yonsei University College of Medicine, Korea. kimsm@yumc.yonsei.ac.kr
- Publication Type:Case Report
- Keywords:
Critical illness;
Myopathy
- MeSH:
Adult;
Atrophy;
Brain;
Critical Illness*;
Diagnosis;
Dyspnea;
Female;
Humans;
Magnetic Resonance Imaging;
Muscular Diseases*;
Myosins;
Pathology;
Quadriceps Muscle;
Quadriplegia;
Respiration, Artificial;
Respiratory Muscles;
Unconsciousness;
Wernicke Encephalopathy
- From:Journal of the Korean Neurological Association
2003;21(6):679-682
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Critical illness myopathy (CIM) is characterized by generalized flaccid weakness occurring in patients with severe systemic illness. A 27-year-old woman presented with loss of consciousness and dyspnea. The brain MRI suggested Wernicke's encephalopathy. During treatment, she experienced progressive quadriparesis and respiratory muscle weakness, which required the mechanical ventilation. The muscle pathology of vastus lateralis revealed type 2 muscle fiber atrophy on histochemical stain and selective loss of myosin on electron microscopic study, and suggested clinical diagnosis of critical illness myopathy.