Production of Re-188.
- Author:
Sang Moo LIM
;
Seung Dae YANG
;
Yong Sup SUH
;
Sang Uk KIM
- Publication Type:Original Article
- Keywords:
Re-188;
W-188/Re-188 generator;
Therapeutic radioisotope;
Double neutron capture reaction
- MeSH:
Aluminum Oxide;
Humans;
Neutrons;
Parents;
Radiotherapy;
Technetium
- From:Korean Journal of Nuclear Medicine
1999;33(2):189-192
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
188Re (beta=22 MeV; gamma=155 keV; T1/2=16.9 hours) is an attractive therapeutic radioisotope which is produced from decay of reactor-produced tungsten-188 parent (T1/2=69 days). 188W has been produced from the double neutron capture reaction of 186W. 188Re can be easily obtained by elution of saline on alumina based 186W/188Re generator, which is commercially available. Complexes labelled with 188Re have been developed for the radiotherapy treatment of diseases because of the desirable nuclear properties of the radioisotope and it's chemical properties similar to those of technetium, a well established diagnostic agent.
