Fatal Acute Hemolytic Transfusion Reaction Due to Anti-E+Fy(a).
- Author:
Kyeong Hee KIM
1
;
Jin Yeong HAN
;
Jeong Man KIM
;
Ki Hyung PARK
;
Kyou Sup HAN
Author Information
1. Department of Laboratory Medicine, Dong-A University College of Medicine, Korea. labmed@damc.or.kr
- Publication Type:Original Article
- Keywords:
Crossmatching test;
Hemolytic transfusion reaction;
Anti-E;
Anti-Fy(a)
- MeSH:
Acute Kidney Injury;
Aged;
Anemia, Refractory;
Antibodies;
Blood Group Incompatibility*;
Erythrocytes;
Fever;
Hemoglobinuria;
Humans;
Hyperbilirubinemia;
Korea;
Mass Screening;
Pulmonary Edema;
Thorax;
Tongue
- From:The Korean Journal of Laboratory Medicine
2003;23(1):57-59
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 72-year-old man with a regrowing tongue mass and refractory anemia received two units of compatible red blood cells by saline and albumin phase crossmatching tests. One hour after the last unit, he had a hemolytic transfusion reaction manifested by chest discomfort, fever, redcolored urine, fall in hemoglobin, hemoglobinuria and bilirubinemia. He developed acute renal failure and pulmonary edema and died three days later. Anti-E+Fy(a) antibodies were identified in the patient's serum. This case suggests that indirect antiglobulin crossmatching tests or antibody screening tests are needed for routine pretransfusion tests in Korea.
