A Case with Cerebral Radiation Necrosis Mimicking Recurrent Brain Tumor.
- Author:
Sang Mok LEE
1
;
Hak Jae NOH
;
Joo Han KIM
;
Woon Gyu PARK
;
Young Joo LEE
;
Kyu Yong LEE
;
Ha Chung CHUN
Author Information
1. Department of Neurology, Hanyang University Hospital.
- Publication Type:Case Report
- Keywords:
Radiation Necrosis;
Brain Tumor;
Biopsy
- MeSH:
Astrocytoma;
Biopsy;
Brain;
Brain Neoplasms*;
Deglutition Disorders;
Edema;
Female;
Follow-Up Studies;
Headache;
Humans;
Magnetic Resonance Imaging;
Nausea;
Necrosis*;
Radiotherapy;
Recurrence;
Seizures;
Vomiting
- From:Journal of the Korean Neurological Association
1999;17(4):597-601
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Regardless of an appropriate radiation therapy administered to a patient with a brain tumor, clinical and radiological evidence of progression may still develop because of a recurrence of the tumor and/or radiation necrosis, or even rarely, a radiation induced neoplasm. The evaluation of tumor recurrence and radiation-induced necrosis presents a diagnostic challenge. A thirty eight year old woman was treated for a focal motor seizure on the right side of her face.with a fractionated external beam radiotherapy under the impression of cystic astrocytoma in the left frontoparietal region. After 6 months, she developed a headache, nausea and vomiting, dysphagia, and secondary generalized seizure. A follow-up brain MRI showed a high signal mass lesion in a T2 weighted image and a fluorodeoxyglucose PET revealed hypometabolism in the left frontoparietal lobe, suggesting radionecrosis. It was confirmed as radionecrosis with an expanding edema by open biopsy. We report a cerebral radiation necrosis mimicking recurrent brain tumor.
