A Case of Spontaneous Pneumothorax During Chemotherapy for Metastatic Choriocarcinoma.
- Author:
Hyang LEE
1
;
Mu Sam KANG
;
Sam Mi LEE
;
Moon Hong KIM
;
Seong Il KIM
;
Seok Cheol CHOI
;
Sang Young RYU
;
Kyung Hee LEE
Author Information
1. Department of Obstetrics and Gynecology, Korea Cancer Center Hospital, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
chemotherapy;
lung metastases;
spontaneous pneumothorax
- MeSH:
Choriocarcinoma*;
Drug Therapy*;
Female;
Humans;
Lung;
Lung Neoplasms;
Neoplasm Metastasis;
Neoplasms, Germ Cell and Embryonal;
Osteosarcoma;
Pneumothorax*;
Pregnancy
- From:Korean Journal of Obstetrics and Gynecology
2002;45(9):1633-1635
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Spontaneous pneumothorax is a rare complication of pulmonary metastatic disease, most often following chemotherapy for osteogenic sarcomas, primary lung cancer or malignant germ cell tumors. Intensive chemotherapy may theoretically increase the risk of pneumothorax in patients with manifest or occult lung metastases by inducing rapid lysis of the tumor tissue and by interfering with repair processes. We present a case of patient with spontaneous pneumothorax after the introduction of chemotherapy for metastatic choriocarcinoma and review the literature and discuss the possible pathophysiologic mechanisms.
