The Effect of Pretreatment with Lidocaine for the Withdrawal Movement Associated with the Injection of Rocuronium in Children.
10.4097/kjae.2002.43.5.572
- Author:
Kyong Sik KIM
1
;
Yun Jeong CHAE
;
Sung Yong PARK
;
Han Bum CHO
;
Jin Soo KIM
Author Information
1. Department of Anesthesiology, School of Medicine, Ajou University, Suwon, Korea. lala06@freechal.com
- Publication Type:Original Article ; Randomized Controlled Trial
- Keywords:
Anesthetic;
local;
lidocaine;
complication;
movement;
neuromuscular relaxants;
rocuronium
- MeSH:
Anesthesia, General;
Child*;
Humans;
Incidence;
Lidocaine*;
Thiopental
- From:Korean Journal of Anesthesiology
2002;43(5):572-574
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: The purpose of this study was two fold; first, to determine the incidence and type of withdrawal movement associated with IV injection of rocuronium in pediatric patients; and second, to determine whether pretreatment with IV lidocaine affects the incidence of movement associated with rocuronium administration in pediatric patients. METHODS: Forty-two pediatric patients were randomly assigned to two groups. After general anesthesia was induced with thiopental sodium 5 mg/kg and manual occlusion of venous inflow was performed, one group of patients received 0.1 ml/kg 1% lidocaine IV. A second group received 0.1 ml/kg of normal saline as a placebo control. Venous inflow occlusion was held for 5 seconds, and immediately followed by the injection of rocuronium 0.6 mg/kg IV. The patient's response to rocuronium injection was graded using a 5-point scale. RESULTS: We observed that the incidence of movement was 100% in the placebo group and was significantly decreased to 28.8% in the group pretreated with lidocaine (P<0.001). CONCLUSIONS: Withdrawal movement on injection of rocuronium in pediatric patients can be decreased or prevented by pretreatment with IV lidocaine.
