Electron microscopic study of adhesion between Helicobacter pylori and gastric epithelial cell.
- Author:
Sung Il LEE
1
;
Hoon Jai CHUN
;
Dong Kyu PARK
;
Young Sun KIM
;
Yoon Hong KIM
;
Jung Whan LEE
;
Byung Won HUR
;
Chang Don KANG
;
Yoon Tae JEEN
;
Hong Sik LEE
;
Chi Wook SONG
;
Soon Ho UM
;
Sang Woo LEE
;
Jai Hyun CHOI
;
Chang Duck KIM
;
Ho Sang RYU
;
Jin Hai HYUN
;
Chang Sub UHM
Author Information
1. Department of Internal Medicine, Institute of Digestive Disease and Nutrition
- Publication Type:Original Article
- Keywords:
Helocobacter pylori;
Gastric cell;
Microscopy, Electron
- MeSH:
Biopsy;
Epithelial Cells*;
Epithelium;
Gastritis;
Helicobacter pylori*;
Helicobacter*;
Humans;
Male;
Membrane Fusion;
Microscopy, Electron;
Pyloric Antrum
- From:Korean Journal of Medicine
2001;60(1):16-21
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: The purpose of this study was to investigate the ultrastructural relation of H. pylori and gastric epithelial cells in their adhesion. METHODS: Endoscopic biopsy of gastric antrum and body was performed from 15 patients (9 men, 6 women) with chronic gastritis. These specimens were processed and observed by transmission electron microscope (Hitachi H-600). RESULTS: On the basis of morphological appearances, the different types of adhesion of the organism with the epithelial cells were categorized as filamentous connection, adhesion pedestals, membrane fusion. Coccoid and intermediate forms were associated with filamentous connection whereas bacillary forms were associated with adhesion pedestals and membrane fusion. CONCLUSION: Various types of adhesion were associated with H. pylori and gastric epithelium. Further studies are needed to investigate biophysiologic influence to epithelial cells by ultrastructural relationship.(Korean J Med 60:16-21, 2001)
