A Case of Toxic Megacolon Associated with Fulminant Pseudomembranous Colitis.
- Author:
Dong Hee KOH
1
;
Hang Lak LEE
;
Jung Mi KIM
;
Won MOON
;
Oh Young LEE
;
Byung Chul YOON
;
Ho Soon CHOI
;
Joon Soo HAHM
;
Chan Kum PARK
Author Information
1. Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea. alwayshang@hanyang.ac.kr
- Publication Type:Case Report
- Keywords:
Toxic megacolon;
Clostridium difficile;
Pseudomembraneous colitis
- MeSH:
Aged;
Clostridium difficile;
Colectomy;
Colitis;
Enterocolitis, Pseudomembranous;
Humans;
Male;
Megacolon, Toxic;
Metronidazole;
Peritonitis;
Pneumonia;
Shock, Septic
- From:Korean Journal of Gastrointestinal Endoscopy
2008;36(2):112-116
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The clinical presentation of Clostridium difficile infection ranges from asymptomatic carriage, colitis with or without pseudomembranes, to fulminant colitis. Although not common, fulminant Clostridium difficile colitis can result in bowel perforation and peritonitis with a high mortality rate. We report a case of toxic megacolon associated with fulminant pseudomembranous colitis. We experienced a case of a 65-year-old male patient who presented with abdominal distension and pain for three days during treatment of pneumonia. We were able to diagnose the case as a toxic megacolon associated with fulminant pseudomembranous colitis. In spite of oral metronidazole treatment and conservative treatment, the clinical course worsened and the patient went into septic shock. The patient underwent a total colectomy but the clinical situation did not improve and the patient died.
