Non-healing Iatrogenic Gastric Ulcers after Endoscopic Mucosal Resection for Gastric Epithelial Neoplasia: Report of Two Cases.
- Author:
Soo Hyeon LEE
1
;
Jae Hee CHEON
;
Jie Hyun KIM
;
Jong Pill PARK
;
Sang Kil LEE
;
Yong Chan LEE
Author Information
1. Department of Internal Medicine and Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Korea. geniushee@yuhs.ac
- Publication Type:Case Report ; English Abstract
- Keywords:
Endoscopic mucosal resection;
EMR-induced ulcer;
Gastric neoplasia;
Helicobacter pylori
- MeSH:
Aged;
Endoscopy, Gastrointestinal;
Gastric Mucosa/pathology/*surgery;
Helicobacter Infections/complications/drug therapy;
Helicobacter pylori;
Humans;
Iatrogenic Disease;
Male;
Middle Aged;
Stomach Neoplasms/complications/diagnosis/*surgery;
Stomach Ulcer/diagnosis/*etiology/pathology
- From:The Korean Journal of Gastroenterology
2008;51(2):127-131
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Endoscopic mucosal resection (EMR) is widely accepted as a standard treatment for early gastric cancer or gastric adenoma. However, EMR inevitably results in the formation of large iatrogenic ulcer at the resected area. Although the characteristics of EMR-induced ulceration are not fully understood, this type of ulcer is thought to heal faster and to recur less often than non-iatrogenic gastric ulcer. Current available evidences have suggested that EMR-induced ulcers heal within 2-3 months. Herein, we report two cases of non-healing persistent gastric ulcers after EMR. One is a case of gastric carcinoma which developed at the same site of previous EMR site for the low grade dysplasia. The other is a case in which persistent EMR-induced ulcer was healed in the long run after Helicobacter pylori eradication therapy.