A Case of Steroid Resistant Autoimmune Hemolytic Anemia in Ulcerative Colitis.
- Author:
Hyun Jong CHOI
1
;
Su Jin HONG
;
Young Jee KIM
;
Bong Min KO
;
Moon Sung LEE
;
Chan Sup SHIM
;
Hyun Jung KIM
;
Dae Sik HONG
Author Information
1. Department of Internal Medicine, Soonchunhyang University School of Medicine, Bucheon, Korea. sjhong@schbc.ac.kr
- Publication Type:Case Report ; English Abstract
- Keywords:
Ulcerative colitis;
Autoimmune hemolytic anemia
- MeSH:
Adult;
Anemia, Hemolytic, Autoimmune/*diagnosis/drug therapy/etiology;
Colectomy;
Colitis, Ulcerative/complications/*diagnosis/pathology;
Drug Resistance;
Female;
Humans;
Splenectomy;
Steroids/therapeutic use
- From:The Korean Journal of Gastroenterology
2008;51(2):137-141
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Autoimmunity is thought to play a central role in the pathogenesis of inflammatory bowel disease and associated extraintestinal manifestations. Autoimmune hemolytic anemia associated with ulcerative colitis is a rare occurrence. No more than 50 cases have been described in the international literatures, and only 2 cases reported in Korea. A 29-year-old woman who was diagnosed as ulcerative colitis two years ago was complicated with autoimmune hemolytic anemia, and did not respond to steroid therapy. Ultimately, total colectomy and splenectomy were carried out for the treatment of ulcerative colitis and hemolytic anemia. After the operation, anemia was resolved. We present the case with a review of literature.
