Relationship Between Anti-HCV with ALT Level and Follow up Study in Anti-HCV Positive Donors.
- Author:
Chung Young LEE
;
Ae Ja PARK
- Publication Type:Original Article
- MeSH:
Blood Donors;
Follow-Up Studies*;
Hepatitis B;
Humans;
Indicators and Reagents;
Prevalence;
Tissue Donors*
- From:Korean Journal of Blood Transfusion
1994;5(1):17-24
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A prevalence of anti-HCV and ALT value was analyzed in 89,995 healthy Korean blood donors. The positive rate of anti-HCV was 0.43% (386) and increased with age. And the positive rates of anti-HCV was statistically significant higher in group having elevated ALT level than in group having normal ALT level(P<0.005). The mixed-infection rates of the hepatitis B and C was 0.02%(25/89,995), and statistically the positivity of anti-HCV was higher in HBs Ag positive group than in HBs Ag negative group(P<0.01). On follow up study from 51 donors of the anti-HCV positivity in initial test, 15(29.4 %) cases were continuously positive by follow up test in 5-20 months. But these results were independent of transfusional history and intervals of follow up. The positive rates of anti-HCV during the follow up with reagents of Ortho- I and Ortho-II were 24% and 33% respectively. The positivity of anti-HCV was higher in group had continuously elevated serum ALT level than in group with normal serum ALT level.
