A Case of Primary Neuroendocrine Carcinoma of Liver Presenting with Liver Abscess.
- Author:
Seuk Hyun LEE
1
;
Kyung Ah KIM
;
June Sung LEE
;
Dong Hoon OH
;
Won Ki BAE
;
Nam Hoon KIM
;
Young Soo MOON
;
Han Seong KIM
Author Information
1. Departments of Internal Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea. kakim@ilsanpaik.ac.kr
- Publication Type:Case Reports ; English Abstract
- Keywords:
Liver abscess;
Liver tumor;
Neuroendocrine carcinoma
- MeSH:
Adenine/analogs & derivatives/therapeutic use;
Antiviral Agents/*adverse effects/therapeutic use;
Drug Eruptions/diagnosis/*pathology;
Female;
Hepatitis B, Chronic/*drug therapy;
Humans;
Ichthyosis/chemically induced/pathology;
Lamivudine/*adverse effects/therapeutic use;
Middle Aged;
Phosphonic Acids/therapeutic use
- From:The Korean Journal of Gastroenterology
2006;48(4):277-280
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Primary hepatic neuroendocrine cell carcinoma is a very rare tumor. We experienced a 75-year-old woman with primary hepatic neuroendocrine carcinoma presenting with pyogenic liver abscess. Abdominal CT scan revealed a multiseptated liver abscess and an enlarged lymph node in portocaval portion. We performed percutaneous drainage of the liver abscess, but the amount of drained pus did not decrease after 20 days. The follow-up abdominal CT scan showed that the cystic portion of liver abscess had been replaced by the solid tumor. Microscopic examination of the tumor tissue showed nests of epithelial cells with uniform round hyperchromatic nuclei and high nuclear to cytoplasmic ratio. Immunohistochemical staining was strongly positive for synaptophysin and chromogranin A.