Main clinical and laboratory characteristics of multiple myeloma (MM)
- Author:
Khoa Dinh Nguyen
- Publication Type:Journal Article
- Keywords:
multiple myeloma
- MeSH:
Multiple Myeloma;
Back Pain;
diagnosis
- From:Journal of Practical Medicine
2002;435(11):19-22
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
A retrospective investigation was carried out during 1991-96 year period on 44 MM patients (27 men and 17 women of the mean age of 52.4 ranged 20-70, admitted to Bach Mai Hospital) diagnosed with R.A. Kyle's critera to review clinic symtoms and laboratory findings. The earliest signes were bone pain (72.3%) including low back pain (65.9%). At advanced stage, bone pain and tenderness (86.4%), anemia (70.5%), weakness of lower limbs (38.6), renal failure (29.5%), increased erythrocyte sedimentation rate (94.4%), hypercalcemia (32.2%), hyperproteinemia (60.7%), proteiuria (61.4%), hypergammaglobulinemia (78.1%), and hyperplasmocytogenesis (92.3%) were reported. 7/12 cases of immunoelectrophoresis had IgG myeloma. Demineralization and compressed vertebral fractures were found in 74.1% of patients. Other common bone lesions were observed radiographiccally in ribs (75%) and skull (72.7%)
